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Overview: Juvmo is used to treat Parkinson’s disease. It works by acting like dopamine in the brain. Common side effects may include nausea, headache, dizziness, tiredness, and change in how things taste. Tell your health care provider right away if you hear or see things that others do not, have strong urges or unusual behaviors, or if you feel faint, lightheaded, or agitated. Also tell your health care provider about all medicines, supplements, and herbal products that you take. Juvmo is a tablet that is taken by mouth.

Uses

What is Juvmo used for?

Juvmo (tavapadon) is commonly used to treat Parkinson’s disease.

Juvmo may also be used for other conditions as determined by your health care provider.

How does Juvmo work (mechanism of action)?

Juvmo is a type of medicine known as a dopamine agonist. It works by acting like a chemical in the brain called dopamine, which may help with symptoms of Parkinson’s disease.

How is Juvmo supplied (dosage forms)?

Brands and other names

  • Juvmo

Dosage forms and strengths

  • 0.25 mg, 1 mg, 5 mg, 10 mg, and 15 mg oral tablets

How should I store Juvmo?

Juvmo should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place.

Side Effects

What are the most common side effects of Juvmo?

The most common side effects of Juvmo are listed below. These side effects may vary depending on whether you are taking Juvmo with other medicines. Tell your health care provider if you have any of these side effects that bother you.

  • Nausea or vomiting
  • Headache
  • Dizziness
  • Tiredness
  • Change in how things taste
  • Dry mouth
  • Anxiety 
  • Uncontrollable, involuntary movements (see below)
  • Hallucinations (see below)
  • Low blood pressure upon standing (see below)

There may be other side effects of Juvmo that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Juvmo?

While less common, the most serious side effects of Juvmo are described below, along with what to do if they happen.

Severe Allergic Reactions. Juvmo may cause allergic reactions, which can be serious. Stop taking Juvmo and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Low Blood Pressure (Hypotension) or Low Blood Pressure Upon Standing (Orthostatic Hypotension). Juvmo may cause low blood pressure. It may also cause a sudden drop in blood pressure when standing up from a seated or lying position. The risk may be higher while you are starting the medicine or increasing the dose. To help prevent this, be careful not to get up too quickly if you are seated or lying down. If you feel dizzy, sit or lie down right away until the dizziness stops, then take your time getting up again. Tell your health care provider right away if you have any of the following symptoms.

  • Dizziness, feeling lightheaded, fainting, or falling
  • Blurred vision
  • Confusion
  • Feeling weak or tired
  • Nausea 
  • Sweating

Unusual or Compulsive Behaviors. Juvmo can cause some people to have strong, unusual, and uncontrolled urges (compulsions), such as feeling like they cannot stop themselves from gambling, having sex, spending money, shopping, or eating. Talk to your health care provider right away if you or someone you know notices that you have new or worsening strong urges or behaviors.

Hallucinations or Psychotic-like Behaviors. Juvmo may cause hallucinations or psychotic-like behaviors. This risk may be higher if you are taking certain other medicines while your dose of Juvmo is being increased. Tell your health care provider right away if you have any of the following symptoms, or if you have been told by others you have these symptoms.

  • Hearing, seeing, smelling, tasting, or otherwise perceiving things that others do not
  • Delusional thoughts, such as false beliefs that you are being controlled
  • Disorganized thoughts, such as jumping between topics or having a hard time focusing
  • Sudden decline in self-care, such as personal hygiene or academic/work performance
  • Aggressive behavior or feeling agitated
  • Confusion
  • Trouble sleeping

Uncontrollable, Involuntary Movements (Dyskinesias). Juvmo may cause or worsen involuntary movement problems, including shakiness, stiffness, or jerkiness. Call your health care provider right away if you have any unusual or uncontrolled movements or if they get worse.

Warnings & Precautions

Who should not use Juvmo?

Allergies to Ingredients. People who are allergic to any of the following should not take Juvmo.

  • Juvmo 
  • Tavapadon
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Juvmo.

What should I know about Juvmo before using it?

Do not take Juvmo unless it has been prescribed to you by a health care provider. Take it as prescribed.

Do not share Juvmo with other people, even if they have the same condition as you. It may harm them.

Keep Juvmo out of the reach of children.

People who are age 65 and older can be at greater risk of some side effects from Juvmo. Talk to your health care provider about your risks if you are in this age group.

What should I tell my health care provider before using Juvmo?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Juvmo is right for you.

In particular, make sure that you discuss any of the following.

Current and Past Health Conditions. Tell your health care provider if you have any of the following.

  • Low blood pressure, including low blood pressure upon standing
  • Mental health problems
  • Hallucinations
  • Unusual urges, such as gambling, binge eating, compulsive shopping, or increased sex drive
  • Uncontrollable, involuntary movements (dyskinesia)

Other Medicines and Supplements. Juvmo may interact with other medicines and supplements. Before taking Juvmo, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Pregnancy. It is not known if or how Juvmo could affect pregnancy or harm a fetus. Tell your health care provider if you are pregnant or plan to become pregnant.

Breastfeeding. It is not known if Juvmo passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should take Juvmo while breastfeeding.

How can I get more information about Juvmo?

For more information about Juvmo, you can visit the drugmaker’s website at www.juvmo.com or call them at 888-817-4847.

Interactions

Does Juvmo interact with foods or drinks?

You should avoid grapefruit and grapefruit juice while taking Juvmo. Grapefruit may increase the amount of Juvmo in your body and raise the risk of side effects.

It is unknown if drinking alcohol will affect Juvmo. The risk of certain side effects, such as dizziness, may be increased if you drink alcohol while taking Juvmo.

Does Juvmo interact with other medicines (drug interactions)?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using or have recently stopped.

In particular, make sure that you discuss if you are using any of the following before taking Lyrfigtu.

  • An antipsychotic, which is a medicine for certain mental health conditions
  • Fluconazole (Diflucan), ketoconazole, itraconazole (Sporanox, Tolsura), posaconazole (Noxafil), or voriconazole (Vfend), which is a medicine used for fungal infections
  • Ciprofloxacin (Cipro), clarithromycin, or Erythromycin (Ery-Tab and others), which is a medicine used for bacterial infections
  • Diltiazem (Cardizem CD and others) or verapamil (Verelan, Verelan PM), which is a medicine used for high blood pressure or other conditions
  • Efavirenz, lopinavir/ritonavir (Kaletra), nelfinavir (Viracept), or ritonavir (Norvir), which is a medicine commonly used to treat HIV
  • Carbamazepine (Carbatrol, Tegretol, and others), phenobarbital, or primidone, which is a medicine commonly used to treat seizures or nerve pain
  • Phenytoin (Dilantin, Phenytek, and others), which is a medicine to control seizures 
  • Rifampin (Rifadin), which is a medicine commonly used to treat an infection called tuberculosis   
  • St. John’s wort, which is a supplement that may be used for depression

Many other medicines may alter the blood levels of Juvmo, and vice versa. Tell your health care provider about all medicines that you take or have recently taken. Let your health care provider know if you stop taking any medicines or supplements.

This may not be a complete list of medicines that can interact with Juvmo. Always check with your health care provider.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Juvmo?

If you or someone else has used too much Juvmo, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Juvmo?

If you miss a dose, take it as soon as you remember on the same day, but do not take double or extra doses. If you do not remember the missed dose until the next day, skip the missed dose and take your next dose at the usual time.